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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRK1
All Species:
23.64
Human Site:
Y415
Identified Species:
43.33
UniProt:
Q15835
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15835
NP_002920.1
563
63526
Y415
I
I
S
E
P
V
K
Y
P
D
K
F
S
Q
A
Chimpanzee
Pan troglodytes
XP_001152241
531
61192
V397
E
K
V
K
W
E
E
V
D
Q
R
I
K
N
D
Rhesus Macaque
Macaca mulatta
XP_001105738
328
37461
V204
G
K
G
G
F
G
E
V
S
A
C
Q
M
K
A
Dog
Lupus familis
XP_542675
460
51324
G336
K
D
P
E
K
R
L
G
F
R
D
G
T
C
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9WVL4
564
63818
Y415
I
I
S
E
P
V
K
Y
P
E
K
F
S
Q
A
Rat
Rattus norvegicus
Q63651
564
63750
Y415
I
I
S
E
P
V
K
Y
P
E
K
F
S
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514822
565
64022
Y415
I
L
S
E
P
V
K
Y
P
E
K
F
S
R
A
Chicken
Gallus gallus
NP_990026
593
64642
Y445
T
L
H
D
S
V
S
Y
S
E
R
F
S
A
A
Frog
Xenopus laevis
NP_001087513
575
66421
Y408
V
K
E
G
Q
E
E
Y
S
A
K
F
S
P
D
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
D309
R
N
T
A
E
M
Y
D
N
I
L
N
K
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P32866
714
80668
Y532
V
K
E
D
P
E
K
Y
S
S
K
F
N
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09537
642
73759
Y425
V
R
E
D
Q
E
K
Y
S
E
K
F
S
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P11792
824
91793
P632
A
F
G
K
V
K
F
P
R
D
V
L
S
Q
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.3
56.4
70.6
N.A.
85.6
86.1
N.A.
77.8
55.3
45
28.9
N.A.
37.5
N.A.
41.9
N.A.
Protein Similarity:
100
64.1
57.7
76
N.A.
94.1
94.1
N.A.
90
68.4
66.2
45.8
N.A.
52.6
N.A.
59
N.A.
P-Site Identity:
100
0
6.6
6.6
N.A.
93.3
93.3
N.A.
80
33.3
26.6
0
N.A.
33.3
N.A.
40
N.A.
P-Site Similarity:
100
20
20
13.3
N.A.
100
100
N.A.
100
60
40
13.3
N.A.
53.3
N.A.
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
16
0
0
0
8
54
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
8
0
24
0
0
0
8
8
16
8
0
0
8
24
% D
% Glu:
8
0
24
39
8
31
24
0
0
39
0
0
0
8
16
% E
% Phe:
0
8
0
0
8
0
8
0
8
0
0
62
0
0
0
% F
% Gly:
8
0
16
16
0
8
0
8
0
0
0
8
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
31
24
0
0
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
8
31
0
16
8
8
47
0
0
0
54
0
16
8
0
% K
% Leu:
0
16
0
0
0
0
8
0
0
0
8
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
8
0
0
8
8
8
0
% N
% Pro:
0
0
8
0
39
0
0
8
31
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
8
0
8
0
31
0
% Q
% Arg:
8
8
0
0
0
8
0
0
8
8
16
0
0
8
0
% R
% Ser:
0
0
31
0
8
0
8
0
39
8
0
0
62
0
0
% S
% Thr:
8
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
24
0
8
0
8
39
0
16
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
62
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _